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Finely crafted nanoparticle products for imaging, microscopy and biodetection

All profits support our cancer research. In the course of our work, we have developed many useful nanoparticle technologies; we hope they are useful in your labs too. 

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    Results: 31 - 40 of 53 products
    GoldiBlot™ procedure and an example of the results, showing detection of His-tagged proteins from a variety of samples.
    GoldiBlot: Ni-NTA-Nanogold® for His Tag Blots

    No more antibodies! Western blots with Ni NTA-Nanogold® direct labeling for His tags. Fast, cheap, archival.

    SilverEnhance developer is deposited around gold nanoparticle labels, growing them for precise, clear visualization in electron microscopy, light microscopy, and western blots.
    HQ Silver Enhancement Kit: Precision Developer for Electron Microscopy

    Precision silver enhancement– the best for EM. Uniform development, excellent structural preservation.

    SilverEnhance developer is deposited around gold nanoparticle labels, growing them for precise, clear visualization in electron microscopy, light microscopy, and western blots.
    LI Silver Enhancement Kits: Precision Developer for EM, LM and Blots

    Precision, nanoparticle silver enhancement: Light insensitive, simple and convenient developer for EM, LM, and western blots.

    Nanogold®-Lipid Conjugates: Each lipid molecule is covalently linked to a 0.8 nm or 1.4 nm Nanogold® cluster through its polar head group. Since the gold moiety is hydrophilic, these molecules retain the amphiphilic nature of the parent lipid, and behave like fatty acids or phospholipids.
    Lipid-Nanogold® Precision Labels

    The versatility of lipids, covalently labeled with Nanogold®. Study membranes by incorporation into the lipid phase, or gold-label micelles and vesicles so that they can be identified and visualized.

    Schematic showing reaction of 12 nm Maleimido Nanogold® with a thiol-functionalized molecule.
    new-solidMaleimido-Nanogold® 12 nm

    Precisely, covalently label any accessible thiol group. Perfect for IgG, IgM, Fab’; proteins and peptides; DNA, RNA, PNA; nanostructured materials and small molecules.

    Schematic showing reaction of 5 nm Maleimido Nanogold® with a thiol-functionalized molecule.
    new-solidMaleimido-Nanogold® 5 nm Labeling Reagent

    Precisely, covalently label any accessible thiol group. Perfect for IgG, IgM, Fab’; proteins and peptides; DNA, RNA, PNA; nanostructured materials and small molecules.

    Structure of 0.8 nm Nanogold® gold nanoparticle (undecagold) showing the [Au11] core, coordinated ligands and peripheral reactive group (maleimide).
    Mono-Sulfo-NHS-Nanogold® 0.8 nm

    Precisely label amines! Nanogold® labels bind covalently, with easy enhancement.

    Left: Silver-enhanced Nanogold®-labeled K+ channel Kv2.1 subunit in rat brain, X15,000 (J.-H. Tao-Cheng, NIH). Right: Darkfield STEM micrographs of Maleimido Nanogold® labeled A β peptide targeting proteasomes; sample was stained with methylamine vanadate. White dots are 1.4 nm Nanogold®. From Gregori, L., Hainfeld, J.F., Simon, M.N., and Goldgaber, D. (1997). Binding of amyloid beta protein to the 20S proteasome. J. Biol. Chem. 272, 58-62.
    Mono-Sulfo-NHS-Nanogold® 1.4 nm

    Precisely label amines! Nanogold® labels bind covalently, with easy enhancement.

    Structure of 0.8 nm Nanogold® gold nanoparticle (undecagold) showing the [Au11] core, coordinated ligands and peripheral reactive group (maleimide).
    Monoamino-Nanogold® 0.8 nm

    Precise, covalently bonded Nanogold® labels for unique sugar or activated carboxyl sites.

    Left: Silver-enhanced Nanogold®-labeled K+ channel Kv2.1 subunit in rat brain, X15,000 (J.-H. Tao-Cheng, NIH). Right: Darkfield STEM micrographs of Maleimido Nanogold® labeled A β peptide targeting proteasomes; sample was stained with methylamine vanadate. White dots are 1.4 nm Nanogold®. From Gregori, L., Hainfeld, J.F., Simon, M.N., and Goldgaber, D. (1997). Binding of amyloid beta protein to the 20S proteasome. J. Biol. Chem. 272, 58-62.
    Monoamino-Nanogold® 1.4 nm

    Precise, covalently bonded Nanogold® labels for unique sugar or activated carboxyl sites.