Superior negative stains for electron microscopy
Nanoparticle precision for the tiniest targets
- Uniform, electron-dense stain for EM
- Dries without crystallization; perfect for EM grids
- Visualize with ease:
- edges of protein complexes
- macromolecules
- cells in suspension
- Better than positive stains like osmium tetroxide:
Won’t obscure labeling of biological structures
Nano-Van™
Based on Vanadium
(Methylamine Vanadate)
For Nanogold® or anywhere a low atomic number light stain is needed
Nano-Van™ (methylamine vanadate) is based on vanadium, which has a lower atomic number (23) than other elements commonly used as negative stain reagents such as uranium (92) or tungsten (74).
Nano-Van™ is recommended for samples labeled with Nanogold®, since it does not obscure visibility of the small 1.4 nm gold as do the higher atomic number stains. It may also be used in other standard negative stain work since it has excellent staining properties (see: Tracz, E., et. al.: Brain Res., 773, 33-44 (1997)).
Features of Nano-Van™
- Produces a light, very uniform negative stain for high-resolution fine structure visualization.
- Stable, non-volatile in the electron beam, more resistant than uranyl acetate.
- Does not denature protein samples.
- Excellent spreading properties.
- Near-neutral pH of 8.
- Supplied ready-to-use as a 2 % solution in water.
- Permits visualization of Nanogold®.